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Lorraine J Gudas Selected Research

Retinoic Acid Receptors (Retinoic Acid Receptor)

3/2022A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes.
1/2022Synthetic Retinoids Beyond Cancer Therapy.
12/2021A retinoic acid receptor β2 agonist attenuates transcriptome and metabolome changes underlying nonalcohol-associated fatty liver disease.
11/2021A Retinoic Acid Receptor β 2 Agonist Improves Cardiac Function in a Heart Failure Model.
1/2019Effects of AM80 compared to AC261066 in a high fat diet mouse model of liver disease.
10/2018Amelioration of Diabetic Nephropathy Using a Retinoic Acid Receptor β2 Agonist.
10/2016A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease.
6/2014Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.
4/2013Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.
1/2011Retinoids, retinoic acid receptors, and cancer.
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Lorraine J Gudas Research Topics

Disease

47Neoplasms (Cancer)
01/2022 - 02/2002
18Carcinogenesis
01/2020 - 03/2002
14Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 09/2002
9Urinary Bladder Neoplasms (Bladder Cancer)
12/2013 - 05/2004
9Carcinoma (Carcinomatosis)
07/2013 - 03/2002
7Acute Promyelocytic Leukemia
01/2022 - 11/2007
6Prostatic Neoplasms (Prostate Cancer)
11/2015 - 03/2002
5Breast Neoplasms (Breast Cancer)
01/2011 - 11/2002
4Liver Diseases (Liver Disease)
03/2022 - 01/2019
4Alcoholism (Alcohol Abuse)
03/2022 - 11/2013
4Kidney Neoplasms (Kidney Cancer)
01/2022 - 10/2003
4Obesity
12/2021 - 01/2009
4Squamous Cell Carcinoma of Head and Neck
01/2020 - 11/2013
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2015 - 01/2004
4Teratocarcinoma
07/2010 - 03/2003
3Leukemia
01/2022 - 04/2013
3Adenocarcinoma
01/2022 - 03/2002
3Neoplasm Metastasis (Metastasis)
12/2021 - 08/2004
3Non-alcoholic Fatty Liver Disease
12/2021 - 10/2016
3Keratomalacia
01/2020 - 10/2010
3Esophageal Squamous Cell Carcinoma
09/2015 - 06/2014
3Lymphatic Metastasis
12/2013 - 12/2011
2Fatty Liver
03/2022 - 12/2021
2Fibrosis (Cirrhosis)
12/2021 - 11/2021
2Hypoxia (Hypoxemia)
11/2021 - 01/2016
2Heart Failure
11/2021 - 01/2018
2Ischemia
11/2021 - 01/2018
2Inflammation (Inflammations)
01/2021 - 01/2019
2Wilms Tumor (Wilm's Tumor)
10/2018 - 02/2013
2Mouth Neoplasms (Oral Cancer)
08/2015 - 10/2010
2Vitamin A Deficiency
01/2015 - 12/2005
2Colorectal Neoplasms (Colorectal Cancer)
06/2013 - 04/2013
2Colonic Neoplasms (Colon Cancer)
06/2013 - 04/2013
1Hepatocellular Carcinoma (Hepatoma)
03/2022
1Alcoholic Liver Diseases (Alcoholic Liver Disease)
01/2022
1Myeloid Leukemia (Leukemia, Myelocytic)
01/2022

Drug/Important Bio-Agent (IBA)

27Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2022 - 02/2002
25RetinoidsIBA
03/2022 - 02/2002
22Proteins (Proteins, Gene)FDA Link
01/2021 - 03/2003
17Vitamin A (Retinol)FDA LinkGeneric
03/2022 - 02/2002
12Messenger RNA (mRNA)IBA
12/2021 - 05/2004
11Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
03/2022 - 06/2003
9lecithin-retinol acyltransferaseIBA
11/2020 - 03/2002
7CarcinogensIBA
09/2015 - 01/2004
6Histone Deacetylase InhibitorsIBA
10/2020 - 03/2005
6Transcription Factors (Transcription Factor)IBA
01/2019 - 11/2003
5Pharmaceutical PreparationsIBA
01/2022 - 12/2009
54- (4- (2- (n- butoxy)ethoxy)- 5- methylthiazol- 2- yl)- 2- fluorobenzoic acidIBA
12/2021 - 10/2016
5AntibodiesIBA
06/2013 - 10/2003
5Retinyl EstersIBA
03/2009 - 03/2002
4RNA (Ribonucleic Acid)IBA
01/2022 - 03/2003
4Polycomb Repressive Complex 2IBA
12/2021 - 04/2013
4Ethanol (Ethyl Alcohol)IBA
01/2021 - 03/2015
4AndrogensIBA
11/2015 - 12/2011
4Androgen Receptors (Androgen Receptor)IBA
11/2015 - 08/2004
4Histones (Histone)IBA
08/2015 - 03/2005
4DNA (Deoxyribonucleic Acid)IBA
01/2011 - 06/2003
4ParaffinIBA
11/2009 - 10/2003
4EnzymesIBA
11/2006 - 03/2002
3Valproic Acid (Depakote)FDA LinkGeneric
01/2022 - 03/2005
3Small Interfering RNA (siRNA)IBA
01/2021 - 04/2013
3LipidsIBA
01/2021 - 11/2011
34-Nitroquinoline-1-oxide (4 Nitroquinoline 1 oxide)IBA
08/2015 - 11/2013
3Biomarkers (Surrogate Marker)IBA
08/2015 - 04/2005
3Lysine (L-Lysine)FDA Link
10/2014 - 12/2011
3Retinoid X Receptors (Retinoid X Receptor)IBA
06/2014 - 11/2003
3Estrogen ReceptorsIBA
07/2013 - 11/2002
3MethyltransferasesIBA
01/2011 - 03/2005
3retinoic acid receptor betaIBA
12/2009 - 03/2004
3Liposomes (Liposome)IBA
09/2007 - 09/2002
2FenretinideIBA
01/2022 - 01/2021
2AntioxidantsIBA
11/2021 - 01/2011
2ErbB Receptors (EGF Receptor)IBA
11/2020 - 01/2004
2VorinostatFDA Link
10/2020 - 10/2008
2Histone Deacetylases (Histone Deacetylase)IBA
10/2020 - 10/2008
2Isotretinoin (Accutane)FDA LinkGeneric
10/2020 - 10/2003
2Bexarotene (LGD1069)FDA Link
01/2019 - 06/2014
2Cyclin D1IBA
12/2013 - 10/2010
2Retinoic Acid 4-Hydroxylase (CYP26B1)IBA
10/2013 - 11/2007
2Estrogens (Estrogen)FDA Link
07/2013 - 01/2011
2Histone MethyltransferasesIBA
06/2013 - 04/2013
23-deazaneplanocinIBA
06/2013 - 04/2013
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2013 - 06/2013
2GlycogenIBA
05/2013 - 11/2011
2retinol dehydrogenaseIBA
01/2012 - 02/2002
2Bromodeoxyuridine (BrdU)IBA
10/2010 - 01/2004
2DecitabineFDA Link
12/2009 - 03/2005
2LecithinsIBA
11/2007 - 05/2004
2Biological ProductsIBA
09/2007 - 10/2003
2InterferonsIBA
09/2007 - 09/2002
1CarbonIBA
01/2022
1Arsenic Trioxide (Trisenox)FDA Link
01/2022
1Mucin-2IBA
01/2022
1Glutathione (Reduced Glutathione)IBA
01/2022
1IsotopesIBA
01/2022

Therapy/Procedure

19Therapeutics
01/2022 - 09/2002
4Drug Therapy (Chemotherapy)
01/2022 - 01/2011
3Cystectomy
07/2013 - 08/2004
2Chemoprevention
01/2011 - 01/2004
1Radiotherapy
01/2022